Amlodipine-Teva 5 mg 30 Tabs
Amlodipine-Teva 5 mg.
Lower blood pressure, eliminate the symptoms of angina pectoris, coronary artery disease and heart failure.
Amlodipine-Teva 5 mg 30 Tabs
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Pharmacotherapeutic group: Selective calcium antagonists with a predominant effect on blood vessels. ATX code С08С А01.
Composition active substance:
amlodipine; 1 tablet contains 6.944 mg of amlodipine besylate, which is equivalent to 5 mg of amlodipine or 13.888 mg of amlodipine besylate, which is equivalent to 10 mg of amlodipine; Excipients: microcrystalline cellulose, anhydrous calcium hydrogen phosphate, sodium starch (type A), magnesium stearate.
Arterial hypertension. Chronic stable angina pectoris. Vasospastic angina (Prinzmetal’s angina). Contraindications Hypersensitivity to dihydropyridines, amlodipine or any other component of the drug. Arterial hypotension of severe degree. Shock (including cardiogenic shock). Left ventricular outflow tract obstruction (eg, severe aortic stenosis). Hemodynamically unstable heart failure after acute myocardial infarction.
hypersensitivity to dihydropyridines, amlodipine or to any other component of the drug; severe arterial hypotension; shock (including cardiogenic shock); obstruction of the outflow tract of the left ventricle (for example, severe aortic stenosis); hemodynamically unstable heart failure after acute myocardial infarction.
Method of administration and dosage:
For admission. The tablets should be taken with a glass of liquid (such as water), with or without food. The break line is designed to better break the tablet for easier swallowing, rather than splitting into two doses.
Adults. For the treatment of arterial hypertension and angina pectoris, the initial dose of the drug is 5 mg, 1 time per day. Depending on the patient’s response to therapy, the dose can be increased to a maximum dose of 10 mg once a day. In patients with angina pectoris, the drug can be used as monotherapy or in combination with other antianginal drugs with resistance to nitrates and / or adequate doses of beta-blockers. There is experience of using the drug in combination with thiazide diuretics, alpha-blockers, beta-blockers or ACE inhibitors in patients with arterial hypertension. There is no need to select a dose of the drug when used simultaneously with thiazide diuretics, beta-blockers and ACE inhibitors.
Children over 6 years of age with arterial hypertension. The recommended starting dose of the drug in this category of patients is 2.5 mg, once a day. If the required blood pressure level is not reached within 4 weeks, the dose can be increased to 5 mg per day. The use of the drug at a dose of 5 mg for this category of patients has not been studied.
Elderly patients. There is no need to select a dose for this category of patients. Increase the dose with caution. Patients with impaired renal function. It is recommended to use the usual doses of the drug, since the concentration of amlodipine in the blood plasma is not associated with the severity of renal failure. THe drug is not excreted by dialysis.
Patients with impaired liver function. Doses of the drug for use in patients with mild to moderate hepatic dysfunction have not been established, therefore, dose selection should be carried out with caution and start using the drug with a low dose. The pharmacokinetics of amlodipine have not been studied in patients with severe hepatic impairment. Patients with severe liver dysfunction should start with a low dose, gradually increasing it.
Experience with deliberate overdose is limited.
Symptoms: the available information suggests that a significant overdose of the drug will lead to excessive peripheral vasodilation and, possibly, reflex tachycardia. The development of significant, and possibly prolonged, systemic arterial hypotension, including fatal shock, has been reported.
Treatment: clinically significant arterial hypotension caused by an overdose of the drug requires active support for the activity of the cardiovascular system, in particular, frequent monitoring of heart and respiratory function, providing the patient with a horizontal position, raising the lower limbs, monitoring the volume of circulating fluid and urination.
To restore vascular tone and blood pressure, vasoconstrictor drugs can be used, making sure that there are no contraindications to their use. Intravenous administration of calcium gluconate may be helpful in mitigating the effects of calcium channel blockade. In some cases, gastric lavage may be helpful. The use of activated charcoal in healthy volunteers within 2 hours after the administration of 10 mg of amlodipine significantly reduced the level of its absorption. Since amlodipine binds to blood proteins to a large extent, the dialysis effect is negligible.
Store at a temperature not exceeding 25 ° C. Store in its original packaging.Produced in Hungary.