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active ingredient: Olmesartan medoxomil; 1 film-coated tablet contains 10 mg of olmesartan medoxomil; excipients: microcrystalline cellulose, low-substituted hydroxypropyl cellulose, lactose monohydrate, hydroxypropyl cellulose, magnesium stearate, titanium dioxide (E 171), talc, hypromelose.
Treatment of essential hypertension in adult patients. Treatment of arterial hypertension in children and adolescents from 6 to 18 years.
Hypersensitivity to the active substance or one of the drug. Pregnant women or women who plan to become pregnant. Obstruction of bile ducts. Concomitant administration of olmesartan medicines containing aliskiren, is contraindicated in patients with diabetes and renal impairment (GFR <60 ml / min / 1.73 m2).
Dosage & Administration
The initial daily dose of olmesartan medoxomil is 10 mg 1 time a day. If blood pressure reduction is insufficient, the dose should be increased to 20 mg 1 time a day. If necessary, the dose can be increased to 40 mg 1 per day (maximum daily dose) or to add to the treatment of hydrochlorothiazide.
The antihypertensive effect of olmesartan medoxomil occurs usually within
2 weeks after starting treatment, and the maximum effect is observed after 8 weeks of therapy. It should be borne in mind when considering changing the dosage regimen for any patient.
In order to enforce the recommended dosage at about the same time each day, with or without food, for example, during breakfast. Tablets should drink plenty of fluids (eg 1 glass of water). The tablet should not be chewed.
Elderly patients (65 years)
Usually there is no need to adjust the dose in elderly patients (see. The recommended dose for patients with renal impairment). When the maximum daily dose to that of 40 mg should be carefully monitored blood pressure.