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active ingredient: carvedilol; 1 tablet contains carvedilol in terms of 100% substance 12.5 mg;
excipients: microcrystalline cellulose; povidone; lactose, monohydrate; potato starch; talc; calcium stearate; mixture for coating “Opadry II Pink” *. * Opadry II Pink Coating Mix contains triacetin; hypromelosis; lactose, monohydrate; titanium dioxide (E 171), polyethylene glycol, iron oxide yellow (E 172); iron oxide black (E 172); erythrosin (E 127); indigo carmine (E 132).
Essential hypertension (as mono- or combination therapy); chronic stable angina, chronic heart failure (additional treatment).
Dosage & Administration
The drug is taken orally, drinking plenty of fluids.
Treatment with Korvasan is held long. Use of the drug should not be stopped abruptly, it is necessary to gradually reduce the dose at weekly intervals. This is especially important for patients with coronary artery disease.
Essential hypertension. The recommended starting dose of 12.5 mg 1 time per day in the first 2 days, then 25 mg 1 time per day. If necessary, increase the dose at intervals of at least 2 weeks, leading up to a maximum recommended dose of 50 mg 1 time a day (or divided into 2 admission).
Chronic stable angina. The recommended starting dose of 12.5 mg 2 times a day during the first 2 days, then – 25 mg 2 times a day.
Chronic heart failure. Dose picked individually under the supervision of a physician. Patients receiving the drug digitalis, diuretics and ACE inhibitors should be stabilized dose of these medications before you start taking Corvasan.
Hypersensitivity to carvedilol or other components of the drug, asthma or chronic obstructive process in the lungs, liver function abnormalities, bradycardia (heart rate <50 bpm. / min), sick sinus syndrome, AV-block II-III degree (if no permanent pacemaker), heart failure in the phase of decompensation (IV functional class NYHA), cardiogenic shock, severe hypotension (systolic blood pressure <85 mm Hg. Art.), metabolic acidosis, Prinzmetal angina, pheochromocytoma, severe violations of peripheral blood circulation, at the same time treatment of verapamil, diltiazem, galactosemia, during pregnancy and lactation.