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1 tablet contains carbimazole 10 mg;
other components: 10 mg tablets: mannitol (E 421), microcrystalline cellulose, corn starch, anhydrous citric acid, sodium starch glycolate (type A), magnesium stearate, iron oxide yellow (E 172).
Antithyroid agents. Sulfur-containing imidazole derivatives. ATX code H03B B01.
Thyroid dysfunction is associated with overproduction of its hormones (hyperthyroidism). Preparation for thyroidectomy in hyperthyroidism. Therapy before and after radioactive iodine treatment.
Dosage and administration:
ESPA-CARB is used only for hyperfunction of the thyroid gland, confirmed by laboratory tests.
The dose at the beginning of treatment should be 20-60 mg, it should be titrated depending on the function of the thyroid gland until the patient is euthyroid, in order to reduce the risk of overtreatment and, as a result, hypothyroidism. Subsequent treatment is carried out in one of two ways. Maintenance therapy: the final dose is usually 5-15 mg / day, which can be taken as a single daily dose. Therapy is continued for at least 6-18 months. Continuous monitoring of thyroid function is recommended along with appropriate dose adjustment to maintain a euthyroid state. Block-replacement regimen: Initial doses of 20-60 mg per day are maintained, and L-thyroxine 50-150 mcg per day is additionally prescribed to prevent hypothyroidism. Therapy lasts at least 6-18 months.
If there are no contraindications or reservations, then such patients do not need a special dosage.
Produced in Germany
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