Herpevir (Aciclovir) 400mg 10 tablets

Pharmacological group: Antiviral agents. ATX code D06B B03.

Composition:

Active ingredient: Aciclovir

1 tablet contains aciclovir in terms of 100% substance 400 mg; excipients: potato starch, povidone, calcium stearate.

Indications:

Treatment of viral infections of the skin and mucous membranes caused by the herpes simplex virus, including primary and recurrent genital herpes; Suppression of f (prevention of recurrence) of infections caused by the herpes simplex virus in patients with normal immunity; Prevention of infections caused by the herpes simplex virus in immunocompromised patients; Treatment of infections caused by the Varicella zoster virus (chickenpox and herpes zoster);

Contraindications:

Hypersensitivity to aciclovir, valacyclovir or other components of the drug.

Method of administration and dosage:

The tablet should be taken whole with water. When using high doses of acyclovir, an adequate level of body hydration should be maintained.

Adults. Treatment of infections caused by the herpes simplex virus.

For the treatment of infections caused by the herpes simplex virus, it is necessary to take aciclovir tablets at a dose of 200 mg 5 times a day at approximately 4-hour intervals, with the exception of the night period. Treatment should be 5 days, but if the primary infection is severe, it can be continued.

For patients with severe immunodeficiency (for example, after bone marrow transplantation) or for patients with reduced absorption in the intestine, the dose can be doubled to 400 mg, or the appropriate dose for intravenous administration can be used.

Treatment should be started as early as possible after the onset of infection. In the case of recurrent herpes, it is better to start treatment in the prodromal period or after the first signs of skin lesions appear.

Prevention of relapse (suppressive therapy) of herpes simplex virus infections. In patients with normal immunity, to prevent recurrence of infections caused by the herpes simplex virus, take aciclovir tablets at a dose of 200 mg 4 times a day with 6 hour intervals.

For convenience, most patients can take 400 mg of aciclovir 2 times a day with 12 hour intervals.

The treatment will be effective even after the abolition of tableted aciclovir up to 200 mg, which should be taken 3 times a day with an 8-hour interval or even 2 times a day with 12 hour intervals.

In some patients, a radical improvement is observed after taking a daily dose of 800 mg acyclovir.

To monitor possible changes in the natural course of the disease, drug therapy should be interrupted periodically at intervals of 6-12 months.

Prevention of herpes simplex virus infections;

To prevent infections caused by the herpes simplex virus, patients with immunodeficiency should take aciclovir tablets at a dose of 200 mg 4 times a day with 6 hour intervals. For patients with significant immunodeficiency (for example, after bone marrow transplantation) or in patients with reduced intestinal absorption, the dose can be doubled to 400 mg, or the appropriate dose for intravenous administration can be used. The duration of prophylaxis depends on the length of the risk period.

Treatment for chickenpox and herpes zoster

For the treatment of infections caused by the viruses of chickenpox and herpes zoster, you need to take aciclovir tablets at a dose of 800 mg 5 times a day at 4-hour intervals, with the exception of the night period. Treatment should continue for 7 days. Patients with severe immunodeficiency (for example, after bone marrow transplantation) or patients with reduced absorption in the intestine are better off using intravenous administration. Treatment should be started as early as possible after the onset of the disease, the result will be better if the treatment is started immediately after the appearance of the rash.

Elderly patients

It should be borne in mind the possibility of impaired renal function in elderly patients, and the dose for them should be changed accordingly (see section “Renal failure”). It is necessary to maintain an adequate level of hydration of the body.

Shelf life: 5 years.

Storage conditions:
Store in its original packaging at a temperature not exceeding 25 °C.

Produced in Ukraine

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