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Lisinopril and Amlodipine Indications:
Essential hypertension in adults.
Substitution therapy in patients with adequate control of blood pressure during simultaneous reception of lisinopril and amlodipine in these doses.
Related to Lisinopril:
– Hypersensitivity to lisinopril or other inhibitors of angiotensin-converting enzyme (ACE);
– A history of angioedema after use of an ACE inhibitor, hereditary or idiopathic angioedema;
– Primary hyperaldosteronism;
– Renal artery stenosis (bilateral or unilateral);
– The application of patients who are on hemodialysis using vysokoprotochnyh membranes (eg AN 69);
– The level of serum creatinine> 220 mmol / L.
– Pregnant women or women planning to become pregnant; lactation (see. section “Pregnancy and lactation”).
Related to Amlodipine:
– Hypersensitivity to amlodipine or other dihydropyridine derivatives;
– Severe hypotension;
– Pronounced stenosis of the aortic or mitral valves or hypertrophic cardiomyopathy with impaired hemodynamics;
– Shock (including cardiogenic shock);
– Hemodynamic heart failure after myocardial infarction (during the first 28 days);
– Acute myocardial infarction;
– Unstable angina (except Prinzmetal angina);
– Hypersensitivity to any of the excipients of the drug.
Dosage & Administration
The recommended dose – 1 tablet per day. The maximum daily dose – 1 tablet.
Due to the fact that food does not affect the absorption of active ingredients, the drug can be used regardless of the meal.
Typically, the drug is combined with a fixed dose should not be used for initial therapy.
Equator drug tablets 10 mg / 5 mg shown only to those patients for whom titrated optimal maintenance doses of lisinopril and amlodipine is 10 mg and 5 mg, respectively. If you need to adjust the dose, dose titration may be considered separate ingredients.
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