Lokren 20mg 28 tablets


Hypertension. Preventing strokes stress.

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Lokren Composition:
active substance: betaxolol;
1 tablet contains betaxolol hydrochloride 20 mg;
Excipients: lactose monohydrate, microcrystalline cellulose, sodium starch glycolate (type A), colloidal anhydrous silica, magnesium stearate; shell: hypromellose, titanium dioxide (E 171), polyethylene glycol.



Preventing strokes stress.


Severe asthma and chronic obstructive pulmonary disease.

Heart failure, which is not controlled by treatment.

Cardiogenic shock.

Atrioventricular block II and III level in patients who have a pacemaker.

Prinzmetal Angina (monotherapy drug is contraindicated in isolated / typical form of the disease).

Sinus dysfunction (including sinoatrial block).

Bradycardia (heart rate <45-50 beats / min).

Severe forms of Raynaud’s syndrome and other disorders of the peripheral circulation.

Untreated pheochromocytoma.


Hypersensitivity to betaxolol.

Anaphylactic reactions in history.

Metabolic acidosis.


Dosage & Administration

The usual dose for hypertension and to prevent angina tension – 1 tablet of 20 mg per day.

The dosage for patients with renal insufficiency. In patients with renal clearance of betaxolol decreases with decreased kidney function.

The dose should be adapted to the condition of kidney patients: with creatinine clearance ³ 20 mL / min dose adjustment is required. However, the recommended clinical monitoring, since the 1st week of treatment to achieve equilibrium drug levels in the blood (an average of 4 days).

For patients with severe renal impairment (creatinine clearance <20 mL / min) the recommended starting dose is 10 mg per day (regardless of frequency and schedule dialysis treatments in patients who performed hemodialysis).

For patients with hepatic impairment is not necessary to adjust the dose; but early treatment is desirable clinical observation.

Children. The safety and efficacy of the drug to children have not been established, therefore its application this category of patients is contraindicated.