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Nitroglycerine Glyceryl trinitrate Composition:
Activity: Glyceryl Trinitrate; 1 tablet contains 0.5 mg nitroglycerin; Auxiliary substances: monohydrate lactose, potato starch; sugar; Crospovidon; magnesium stearate.
Relief and short-term prevention of angina attacks.
Hypersensitivity to nitroglycerin, drug auxiliary components, nitrates.
Cerebral ischemia, cardiac tamponade, hypertrophic obstructive cardiomyopathy, concomitant use of sildenafil and other inhibitors of phosphodiesterase, hypotension (systolic blood pressure (BP) below 100 mmHg.
Diastolic blood pressure below 60 mm Hg), Increased intracranial pressure (in t. h. at hemorrhagic stroke, after a recent head trauma), angle-closure glaucoma with high intraocular pressure.
Vascular collapse, shock, acute myocardial infarction, accompanied by a decrease in left ventricular filling pressure (isolated mitral stenosis, constructive pericarditis), bradycardia (less than 50 beats / min).
Dosage & Administration.
Angina. You should take nitroglycerin sublingual immediately after the onset of an attack. Usual dose – 1 tablet, for many patients with stable angina and less effective the dose. Therefore, if the pain is soon cut off, the rest pills that had no time to completely dissolve, spit recommended. In the absence of antianginal action within the first 5 minutes should take 1 pill.
In the absence of therapeutic effect after taking 2-3 tablets should seek medical advice immediately (chance of developing myocardial infarction);
Nitroglycerin is valid for 30 minutes. With frequent strokes advisable to prescribe drugs nitrohlitserynovoho prolonged series. However, if angina develops during prolonged treatment with nitrates, to relieve acute attack should use nitroglycerin. Tolerance to sublingual nitroglycerin form occurs rarely, but with its origin in some patients the dose should be gradually increased, bringing it to 2-3 tablets.