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Noliprel Forte Composition:
active ingredients: perindopril arginine, indapamide; 1 tablet contains 5 mg of perindopril arginine, which corresponds to 3.395 mg of perindopril and 1.25 mg of indapamide;
excipients: lactose monohydrate, magnesium stearate (E 470 B), maltodextrin, colloidal silicon dioxide (E 551), sodium starch (type A), macrogol 6000, glycerin (E 422), hypromellose (E 464), titanium dioxide (E 171).
Pharmacotherapeutic group: Perindopril and diuretics. Code ATX C09B A04.
Treatment of essential hypertension in adult patients. Noliprel arginine forte is indicated if additional control of blood pressure is required when perindopril is used as monotherapy.
Dosage and administration:
For oral use. The recommended dose of the drug Noliprel forte is 1 tablet per day, preferably in the morning before meals. An individual selection of the dose of the individual components of the drug may be recommended. In the case of clinical expediency, it is possible to switch from monotherapy immediately to treatment with Noliprel arginine forte.
Special categories of patients
Elderly patients (see Section “Peculiarities of use”). Treatment should be started based on blood pressure and kidney function.
Impaired kidney function (see Section “Peculiarities of use”). In the presence of severe renal dysfunction (creatinine clearance <30 ml / min), treatment with the drug is contraindicated. For patients with moderate renal impairment (creatinine clearance 30-60 ml / min), it is recommended to start treatment with adequate doses of the individual components of the drug. Patients with creatinine clearance ≥ 60 ml / min do not require dose adjustment. Routine medical supervision should include frequent monitoring of plasma creatinine and potassium levels.
Impaired liver function (see sections “Contraindications”, “Peculiarities of use” and “Pharmacokinetics”). In the presence of severe liver dysfunction, treatment is contraindicated. Patients with moderate hepatic impairment do not require dose adjustment.
Shelf life: 3 years
Produced in France
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