Preductal MR 35mg 60 tablets

$38.00

For adults, trimetazidine is indicated for the symptomatic treatment of stable angina in case of insufficient efficacy or intolerance to first-line antianginal drugs.

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Description

Preductal MR Composition:
active substance: trimetazidine;1 tablet contains: trimetazidine dihydrochloride 35 mg;
excipients:tablet: calcium hydrogen phosphate dihydrate, hypromellose 4000, magnesium stearate, povidone, colloidal anhydrous silica;shell: glycerin, macrogol 6000, magnesium stearate, hypromellose, iron oxide red (E 172), titanium dioxide (E 171).
Pharmacotherapeutic group:
Cardiac drugs. Trimetazidine. ATX code C01E B15.
Indication:
For adults, trimetazidine is indicated for the symptomatic treatment of stable angina in case of insufficient efficacy or intolerance to first-line antianginal drugs.
Contraindication:
Hypersensitivity to the active substance or to any of the excipients. Parkinson’s disease, symptoms of parkinsonism, tremor, restless legs syndrome and other movement disorders related to the above. Severe renal insufficiency (creatinine clearance <30 ml / min).
Method of application and dosage:
For oral use. 1 tablet of 35 mg trimetazidine 2 times a day, morning and evening, with meals.
After 3 months of treatment, the results of treatment should be evaluated and in the absence of effect, trimetazidine should be discontinued.
Special groups of patients
Patients with renal insufficiency For patients with moderate renal impairment (creatinine clearance 30-60 ml / min), the recommended dose is 1 tablet per day in the morning at breakfast (see section 4.4) and pharmacokinetics.
Elderly patients Elderly patients may have an increase in trimetazidine levels due to age-related decline in renal function (see Pharmacokinetics). For patients with moderate renal impairment (creatinine clearance 30-60 ml / min), the recommended dose is 1 tablet of 35 mg in the morning at breakfast. For elderly patients, the dose should be titrated with caution (see section 4.4).
Shelf life: 3 years