Tempalgin (Metamizole) 10 tabs
Pharmacotherapeutic group: Analgesics. Pyrazolones. Metamizole sodium, combinations with psycholeptics. ATX code N02B B72.
active ingredients: metamizole sodium monohydrate, tempidone (triacetonamine-4-toluenesulfonate);
1 coated tablet contains: metamizole sodium monohydrate 500 mg, tempidone (triacetonamine-4-toluenesulfonate) 20 mg;
excipients: wheat starch, microcrystalline cellulose (type 101), povidone K 25, talc, magnesium stearate; film coating: Opadry II 85 F21526 green (partially hydrolyzed polyvinyl alcohol, macrogol 3350, talc, titanium dioxide (E 171), quinoline yellow (E 104), brilliant blue FCF (E 133)).
For short-term symptomatic treatment of pain syndrome, from mild to moderate, in the following conditions: headache, toothache and dental manipulations, myalgia, neuralgia, arthralgia.
- Hypersensitivity to active or excipient substances;
- hypersensitivity to other pyrazolone derivatives;
- acute hepatic porphyria;
- congenital insufficiency of glucose-6-phosphate dehydrogenase (threat of hemolysis);
- severe kidney and / or liver disease;
- dysfunction of the bone marrow (for example, after treatment with cytostatics);
- diseases of the blood system (aplastic anemia, leukopenia and agranulocytosis), changes in the peripheral blood composition;
- anemia of any etiology, cytostatic or infectious neutropenia;
- arterial hypotension with blood pressure values below 100 mm Hg. Art .;
- suspicion of acute surgical pathology.
The tablets are taken orally with water, preferably after meals. The course of treatment should not be more than 3 days. Application for a longer period of time or in higher doses is possible only after consulting a doctor. The dose depends on the severity of the pain and on the individual sensitivity to the drug.
The usual dose is 1 tablet 1-2 times a day, depending on the severity of the clinical symptoms. The maximum single dose should not exceed 1 tablet. The maximum daily dose is 2 tablets. For dental procedures, 1 tablet 30 minutes before the intervention.
1 tablet per day. The maximum daily dose is 1 tablet.
No dose reduction is usually required. In patients with age-related impairment of kidney and liver function, treatment with the drug should be short-lived. The maximum daily dose should not exceed 2 tablets.
In these patients, an increase in the half-life of metamizole metabolites is possible. In patients with moderate or severe liver damage, treatment with ½ the recommended dose for adults is recommended (maximum daily dose is 1 tablet).
Metamizole and its metabolites are excreted by the kidneys. In patients with impaired renal function, treatment with Tempalgin should be carried out using ½ the recommended dose for adults (the maximum daily dose is 1 tablet).
Do not use in children under 15 years of age.
Metamizole sodium has analgesic and anti-inflammatory effects. It inhibits the synthesis of prostaglandins, suppressing cyclooxygenase, has a membrane stabilizing effect, and inhibits the formation of endogenous pyrogens.
Tempidone has a pronounced anxiolytic activity and relieves anxiety, fear and tension. Reduces motor excitement, has a central N-anticholinergic effect. Strengthens and lengthens the analgesic effect of metamizole. Tempidone has a beneficial effect on the emotional component of pain. The combination of metamizole sodium and tempidone enhances the analgesic effect of metamizole and increases the duration of its action.
Use during pregnancy or lactation Pregnancy.
Controlled clinical studies in pregnant women have not been conducted, there are no observational data on the use of the drug by this group. Despite the fact that metamizole is a weak inhibitor of prostaglandin synthesis, there is a possibility of premature closure of the Botallovian duct and perinatal complications as a result of a decrease in platelet aggregation in the fetus and mother. Treatment with the drug is contraindicated in pregnant women.
Lactation. Metamizole metabolites pass into breast milk. If treatment with Tempalgin is necessary, breastfeeding should be discontinued.
Store in a dark place and out of reach of children at a temperature not exceeding 25 ºС
Produced in Ukraine