Tizanidine 4mg 30 tabs – Free Shipping


Muscle relaxant, antispasmodic. Free International Shipping

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Tizanidine 4mg 30 tabs

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Pharmacotherapeutic group:
Muscle relaxants of central action.ATX code M03B X02.

active substance: tizanidine;
1 tablet contains 4 mg tizanidine; excipients: microcrystalline cellulose, anhydrous lactose, anhydrous colloidal silicon dioxide, stearic acid.

  • Painful muscle spasm.
  • Spasticity due to multiple sclerosis.
  • Spasticity due to spinal cord injury.
  • Spasticity due to brain damage.
  • Hypersensitivity to tizanidine or any excipients of the drug.
  • Severe liver dysfunction.
  • Concomitant use of tizanidine with potent inhibitors of CYP1A2, such as fluvoxamine or ciprofloxacin.
Method of administration and dosage:
Tizalud has a narrow therapeutic range and high variability in plasma drug concentration in different patients. Therefore, it is important to use optimal doses according to the patient’s needs. Treatment should be started with a low dose of 2 mg, which minimizes the risk of adverse effects from taking the drug. If necessary, the dose of the drug should be gradually increased with all necessary precautions.
Relief of Painful Muscle Spasms Apply 2-4 mg 3 times a day. In severe cases, an additional dose of 2 or 4 mg may be taken before bedtime.
Spasticity in neurological disorders:
The dose must be selected individually for each patient. The initial daily dose should not exceed 6 mg, divided into 3 doses. It can be increased to 2-4 mg twice gradually at intervals of 3-7 days. As a rule, the optimal therapeutic effect is achieved with a daily dose of 12-24 mg, divided into 3 or 4 doses. The total daily dose of 36 mg should not be exceeded.
Special patient populations:
Application for children and adolescents: The experience of using the drug Tizalud for children and adolescents is limited, therefore the drug is not recommended for use in children and adolescents.
Elderly patients: The experience of using the drug in elderly patients is limited, therefore, caution should be exercised when using the drug Tizalud in this category of patients. It is recommended to start treatment with the lowest dose and gradually increase it with caution in “small steps” until the optimal balance of individual tolerance and therapeutic efficacy of the drug is achieved.
Use in patients with impaired renal function: For patients with impaired renal function (CC <25 ml / min), the recommended initial single daily therapeutic dose is 2 mg. The dose is increased gradually and with caution in “small steps” until the optimal balance of individual tolerance and therapeutic efficacy of the drug is achieved. In order to increase the therapeutic efficacy, you should first increase the single dose before moving on to a more frequent daily intake of the drug.
Use in patients with impaired liver function: Treatment of patients with severe liver dysfunction is contraindicated. Tizalud is extensively metabolized in the liver. The drug should be used with caution in the treatment of patients with moderately severe liver dysfunction. Treatment should be started with the lowest dosage; it is possible to increase the dose with caution and taking into account the patient’s individual tolerance of the drug Tizalud.
Interruption of treatment: If necessary, interruption of drug treatment should be reduced slowly and gradually. This is especially true for patients who have received an increased dose of the drug for a long time. Thus, the risk of developing a rebound increase in blood pressure and tachycardia is reduced.
The ability to influence the reaction rate when driving or operating machinery:
Tizanidine can cause drowsiness, dizziness and / or arterial hypotension, thus impairing the patient’s ability to drive or operate machinery. The risks increase with the simultaneous use of alcohol. Therefore, one should refrain from activities that require a high concentration of attention and quick reactions, for example, driving vehicles or working with machines and mechanisms.
Shelf life: 3 years.
Storage conditions:
Store at a temperature not exceeding 30 ° C, out of the reach of children.
Produced in Ukraine

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