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Epilepsy. As monotherapy for treatment of patients with newly diagnosed epilepsy or for the transition of patients with epilepsy on monotherapy.
As adjunctive therapy for the treatment of adults and children over the age of 3 years, with partial or generalized tonic-clonic seizures.
As adjunctive therapy for the treatment of adults and children with seizures associated with Lennox – Gastaut syndrome.
Migraine. For the prevention of migraine in adults.
Hypersensitivity to any component of the drug; pregnancy and breastfeeding.
Dosage & Administration
Иoth adults and children, it is recommended to start treatment with the lowest dose with further gradual selection of effective dose.
The drug can be taken regardless of meals.
Adults. dose selection should begin with 25 mg topiramate reception at night during the week. Further dose can be increased to 25-50 mg for 1 or 2 weeks and taking it in 2 hours. If the patient does not have time to adapt to the increase in dose must be less than or significantly increase the dose to withstand longer intervals between elevations. When selecting a dose guided therapeutic efficacy.
Children over the age of 3 years. Treatment for children from 3 years of age should begin with reception of 0.5-1 mg / kg of topiramate at night for 1 week. Further dose can be increased by 0.5-1 mg / kg / day at intervals of one or two weeks; the daily dose can be divided into 2 doses. If the child can not adapt to the recommended dose regimen selection, you can use a less significant increase in dose or withstand longer intervals between them increase. In the selection of doses should be guided by the therapeutic efficacy.
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