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Ursodeoxycholic acid Indications
Dissolution of cholesterol gallstones is not more than 15 mm in diameter, provided the functioning of the gallbladder;
Primary biliary cirrhosis (PBC) in the absence of decompensated liver cirrhosis;
gastritis with bile reflux.
Dosage & Administration
Ursodeoxycholic acid adults administered orally, without chewing, drinking plenty of fluids (can be during a meal). The daily dose is usually taken 1 time a day at bedtime, in some cases, to enhance the effect holeliticheskogo – 2 times a day.
Dosage regimen is individual:
to dissolve gallstones in a dose of 10 mg / kg of body weight per day taken from 6 months to 2 years. If after 12 months of treatment, a decrease not gallstones, further use of the drug is inappropriate. Treatment efficacy is monitored by ultrasound or X-ray every 6 months. With the development of calcification of stones treatment ceased;
for the treatment of gastritis with bile reflux appoint 300 mg (1 capsule) Choludexan bedtime; the duration of treatment is usually 10-14 days;
Hypersensitivity to the drug; acute cholecystitis; acute cholangitis; non-functioning gall bladder;
gallstone disease with a high calcium content in the calculi; empyema of the gallbladder; bile-intestinal fistula; inflammation of the small and large intestines; cirrhosis of the liver in the stage of decompensation; liver and / or kidney failure; pancreatitis; children weighing less than 35 kg; During pregnancy and breastfeeding.
The capsules should not be used as Choludexan with obstruction of the bile duct (common bile duct or duct bladder). Choludexan not indicated for patients with gall bladder, which is not visualized by radiological methods, in violation of the contractile function of the gallbladder, or those who have frequent biliary colic.