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Composition:
active ingredient: verapamil hydrochloride; 1 capsule contains verapamil hydrochloride 180 mg in the form of prolonged release pellets; excipients in the composition of the pellet: spherical sugar, shellac, povidone, talc hard gelatin capsule No. 1: sunset yellow (E 110), quinoline yellow (E 104), titanium dioxide (E 171), gelatin.
Indications
Arterial hypertension. Ischemic heart disease, including stable exertional angina, unstable angina (progressive angina, rest angina), vasospastic angina (variant angina, Prinzmetal’s angina), post-infarction angina in patients without heart failure, unless b-blockers are indicated. Arrhythmias: paroxysmal supraventricular tachycardia, atrial flutter/fibrillation with fast AV conduction (with the exception of Wolff-Parkinson-White (WPW) syndrome).
Dosage & Administration
Doctor chooses the dose individually. The average daily dose for all indications is 180-360 mg. At the beginning of treatment prescribed 1 capsule (180 mg), 1 per day, in the morning. If necessary, increase the dose to 360 mg / day (1 capsule in the morning and evening, with an interval of about 12 hours between doses). Exceeding the dose is only possible for a very short time and under the close supervision of a physician.
Ppatients with impaired liver function, depending on the severity, the action of verapamil hydrochloride is amplified and lengthened due to the slowdown in drug dissolution. Therefore, in such cases, the dosage should be set with extreme caution, and to start with low doses (eg 2-3 times per day to 40 mg, respectively, 80-120 mg / day). Use the drug verapamil with this dosage.
Verapamil can be taken before, during or after a meal, without chewing or dissolving, with a little water.
Contradictions
– hypersensitivity to verapamil or any other components of the drug;
– cardiogenic shock;
– acute phase of myocardial infarction with complications (. bradycardia <50 beats / min, arterial hypotension (systolic blood pressure below 90 mm Hg), left ventricular failure..);
– severe conduction abnormalities: sinoatrial and AV blockade II-III degree (except for patients with artificial pacemaker);
– syndrome sick sinus (except for patients with artificial pacemaker);
– congestive heart failure;
– flicker / atrial flutter (compared with WPW-syndrome and Lown ma – Genome – Levine (LGL) Simultaneous in / in a .beta.-adrenergic receptor blockers (except for intensive care)..
– pregnancy and breastfeeding.
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