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active ingredient: verapamil; 1 ml of solution contains verapamil hydrochloride 2.5 mg; excipients: sodium chloride, citric acid, monohydrate, sodium hydroxide, diluted hydrochloric acid (1 M), water for injection.
Paroxysmal supraventricular tachycardia; atrial flutter/fibrillation (with the exception of Wolff-Parkinson-White syndrome (WPW)). Unstable angina in patients who are contraindicated in nitrates and / or β-blockers, including vasospastic angina, variant angina, Prinzmetal’s angina. Arterial hypertension; hypertensive crisis. In pediatric practice – with paroxysmal supraventricular tachycardia.
Hypersensitivity to the drug. Atrioventricular blockade II-III degree. Hypotension. sick sinus syndrome (except in patients with a pacemaker). The syndrome of Wolff-Parkinson-White syndrome or Lown-Genonta-Levine in conjunction with atrial flutter or atrial fibrillation. Severe aortic stenosis. Myocardial infarction with left ventricular failure. Tachycardia with a wide QRS complex. Severe functional insufficiency of the liver and / or kidneys. Ischemic or hemorrhagic stroke.
Dosage & Administration
Applied as a slow intravenous injection or infusion. The infusion solution is prepared from 5 mg of verapamil at 150 ml 0.9% sodium chloride solution. The starting dose for adults and children over 14 years of age is 5 mg, which is administered bolus over 2-5 minutes under the supervision of electrocardiographic and blood pressure monitoring. In the absence of the effect of the introduction of the drug should be repeated after 5-10 minutes. Maintenance dose is administered as an infusion of 5-10 mg per hour. The daily dose should not exceed 100 mg.
The dose of verapamil for infants: 0.75-2 mg for children 1-5 years – 2-3 mg for children 6- 14 years – 2.5-5 mg.
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